Written by: Jonathan Alsop, PhD | Posted on: | Category: MAIC

Matching-adjusted indirect comparison of palbociclib versus ribociclib and abemaciclib in hormone receptor-positive/HER2-negative advanced breast cancer

This recently published MAIC is an interesting one. The authors have clearly gone to great lengths to identify and adjust for potential treatment-effect ...

Read More
Missing data
Written by: Jonathan Alsop, PhD | Posted on: | Category: RWD/RWE

Missing inaction?

Just read a nice Q&A article from Murtuza Bharmal on the increased use of RWD/RWE.

The point he makes on "ensuring minimal missing data" is certainly critical to the external validity of real world ...

Read More
Written by: Jonathan Alsop, PhD | Posted on: | Category: Estimands

Study protocol - you’re either with me or against me!

When it comes to assessing the impact of how well patients (and arguably centres) in a randomised clinical trial follow the protocol, the standard method for some decades has been via the identification of the ‘Per Protocol’ ...

Read More
Written by: Jonathan Alsop, PhD | Posted on: | Category: HTA

That would make a NICE change….

NICE are currently undergoing what appears to be quite a wide re-evaluation of their HTA process. As part of this process, they have recently released a white paper for comment, entitled “The NICE methods of health technology ...

Read More
Categories
RapidWeaver Icon

Made in RapidWeaver